ICD-11 classes
12 Diseases of the respiratory system
Certain lower respiratory tract diseases
CA21 — Emphysema

ICD-11 CA21 — Emphysema

Emphysema is defined by abnormal and permanent enlargement of the airspaces that are distal to the terminal bronchioles. This is accompanied by destruction of the airspace walls, without obvious fibrosis (i.e. there is no fibrosis visible to the naked eye). Emphysema can exist in individuals who do not have airflow obstruction; however, it is more common among patients who have moderate or severe airflow obstruction.

The diagnosis includes nothing.

It excludes 8 items.

  • Compensatory emphysema (CB40.4)
  • Interstitial emphysema originating in the perinatal period (KB27.0)
  • emphysema due to inhalation of chemicals, gases, fumes or vapours (CA81)
  • emphysema mediastinal (CB40.3)
  • Traumatic subcutaneous emphysema, not elsewhere classified (NF0A.7)
  • emphysema, surgical (subcutaneous) (NE81)
  • emphysema with chronic (obstructive) bronchitis (CA22)
  • emphysematous (obstructive) bronchitis (CA22.1)

Diagnosis with code CA21 contains 5 clarifying diagnoses:

  1. CA21.0 — MacLeod syndrome
  2. CA21.1 — Panlobular emphysema
  3. CA21.2 — Centrilobular emphysema
  4. CA21.Y — Other specified emphysema
  5. CA21.Z — Emphysema, unspecified

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