ICD-11 classes
14 Diseases of the skin
Genetic and developmental disorders affecting the skin
Chromosomal disorders affecting the skin
LD50.3 — Klinefelter syndrome
ICD-11 LD50.3 — Klinefelter syndrome
Klinefelter syndrome defines a group of chromosomal disorders in which there is at least one extra X chromosome compared with the normal 46,XY male karyotype. The effects on physical features and on physical and cognitive development increase with the number of extra X's, and each extra X is associated with an intelligence quotient (IQ) decrease of approximately 15-16 points, with language most affected, particularly expressive language skills.
The diagnosis includes nothing.
The diagnosis excludes nothing.
Diagnosis with code LD50.3 contains 3 clarifying diagnoses:
- LD50.30 — Klinefelter syndrome with karyotype 47,XXY, regular
- LD50.31 — Klinefelter syndrome, male with more than two X chromosomes
- LD50.3Y — Other specified Klinefelter syndrome
The diagnosis is coded elsewhere:
- Number anomalies of chromosome X #23702
- Klinefelter syndrome #23711