ICD-11 classes
14 Diseases of the skin
Skin disorders involving certain specific body regions
Skin disorders involving the head and neck
Dermatoses of the lips or oral cavity
DA01 — Disorders of oral mucosa
DA01.2 — Granuloma or granuloma-like lesions of oral mucosa
DA01.21 — Orofacial granulomatosis

ICD-11 DA01.21 — Orofacial granulomatosis

Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterised by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa (the latter resulting in a «cobblestone» appearance), oral ulceration and the presence on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn disease, sometimes presenting months or years before bowel disease. Some cases are associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with fissured tongue and facial palsy (Melkersson-Rosenthal syndrome).

The diagnosis includes nothing.

The diagnosis excludes nothing.

It has no clarifying diagnoses.

The diagnosis is coded elsewhere:

• Granuloma or granuloma-like lesions of oral mucosa #13270