ICD-11 classes
14 Diseases of the skin
Skin disorders involving certain specific body regions
Skin disorders involving the genital and perianal regions
Dermatoses of female genitalia
2C70 — Malignant neoplasms of vulva
2C70.2 — Squamous cell carcinoma of vulva

ICD-11 2C70.2 — Squamous cell carcinoma of vulva

An invasive squamous cell carcinoma arising from the vulva. Risk factors include the human papilloma virus and cigarette smoking. Precursor lesions include the vulvar intraepithelial neoplasia, lichen sclerosus with associated squamous cell hyperplasia, and chronic granulomatous vulvar disease such as granuloma inguinale. Symptoms include vulvar pruritus or irritation, discharge, bleeding, and pain. The following morphologic variants have been identified: keratinizing, non-keratinizing, basaloid, warty, verrucous, keratoacanthoma-like, and squamous cell carcinoma with tumour giant cells. Risk factors for recurrence include advanced stage, tumour diameter greater than 2.5 cm, multifocality, capillary-like space involvement, associated vulvar intraepithelial neoplasia grades 2 or 3, and margins of resection involved by tumour.

The diagnosis includes nothing.

The diagnosis excludes nothing.

It has no clarifying diagnoses.

The diagnosis is coded elsewhere:

• Malignant neoplasms of vulva #2250
• Malignant neoplasms of vulva #19200