ICD-11 classes
14 Diseases of the skin
Malignant neoplasms involving the skin
In situ neoplasms of skin
2E64 — Carcinoma in situ of skin
2E64.0 — Intraepidermal squamous cell carcinoma
ICD-11 2E64.0 — Intraepidermal squamous cell carcinoma
Malignant squamous neoplasia confined to the epidermis of extragenital skin and known commonly as Bowen disease. It arises most frequently on chronically sun-exposed glabrous skin of the head and neck or lower legs. It typically presents as single or multiple well-demarcated scaly erythematous patches, nodules or plaques which histologically show extensive keratinocytic atypia. It may develop from preexisting actinic keratosis (Actinic intraepidermal squamous cell carcinoma). Although it is most commonly associated with exposure to ultraviolet radiation, other carcinogens such as arsenic and tar may be implicated. Human papilloma virus may represent an additional risk factor in immunosuppressed patients.
The diagnosis includes nothing.
The diagnosis excludes nothing.
Diagnosis with code 2E64.0 contains 4 clarifying diagnoses:
- 2E64.00 — Bowen disease of skin
- 2E64.01 — Actinic intraepidermal squamous cell carcinoma
- 2E64.0Y — Other specified intraepidermal squamous cell carcinoma
- 2E64.0Z — Intraepidermal squamous cell carcinoma, unspecified
The diagnosis is coded elsewhere: