ICD-11 classes
02 Neoplasms
Malignant neoplasms, except primary neoplasms of lymphoid,...
Malignant neoplasms, stated or presumed to be primary, of...
Malignant neoplasms of lip, oral cavity or pharynx
2B68 — Malignant neoplasms of submandibular or sublingual glands

ICD-11 2B68 — Malignant neoplasms of submandibular or sublingual glands

Salivary gland tumours can show a striking range of morphological diversity between different tumour types and sometimes within an individual tumour mass. In addition, hybrid tumours, dedifferentiation and the propensity for some benign tumours to progress to malignancy can confound histopathological interpretation. These features, together with the relative rarity of a number of tumours, can sometimes make diagnosis difficult, despite the abundance of named tumour entities. The increasing use of pre-operative fine needle aspiration biopsies also needs to be taken into account, as artifactual changes may be superimposed on the tumours. Unfortunately, the morphological variability of these tumours is mirrored by the immunocytochemical profiles, so that special stains are rarely useful in routine diagnosis of salivary gland epithelial neoplasms.

The diagnosis includes nothing.

Diagnosis with code 2B68 contains 4 clarifying diagnoses:

1. 2B68.0 — Adenocarcinoma of submandibular or sublingual glands
2. 2B68.1 — Squamous cell carcinoma of submandibular or sublingual glands
3. 2B68.2 — Other specified malignant neoplasms of submandibular or sublingual glands
4. 2B68.Z — Malignant neoplasms of submandibular or sublingual glands, unspecified