ICD-11 classes
16 Diseases of the genitourinary system
Diseases of the male genital system
Dermatoses of male genitalia
Premalignant or malignant disorders of the penis or scrotum
2E67.4 — Carcinoma in situ of penis

ICD-11 2E67.4 — Carcinoma in situ of penis

This comprises both squamous carcinoma in situ and extramammary Paget disease of the penis. The former is an uncommon precancerous disease of penile skin. Lesions usually appear on the glans or inner aspect of the foreskin and are almost always found in uncircumcised men. If left untreated, 10-30% of cases develop into invasive squamous cell carcinoma of the penis. When it affects the skin of the shaft or prepuce it is commonly called Bowen disease. If it affects the glans or inner surface of the prepuce it may also be referred to as penile intraepithelial neoplasia (or in the past as erythroplasia of Queyrat). Extramammary Paget disease of penis is a rare form of carcinoma in situ involving penile skin or glans penis.

The diagnosis includes nothing.

The diagnosis excludes nothing.

Diagnosis with code 2E67.4 contains 2 clarifying diagnoses:

  1. 2E67.40 — Squamous cell carcinoma in situ of skin of penis
  2. 2E67.41 — Squamous cell carcinoma in situ of mucocutaneous epithelium of penis

The diagnosis is coded elsewhere:

The diagnosis is included in 1 another class.

  • Extramammary Paget disease of penis (2E64.1)

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