ICD-11 classes
16 Diseases of the genitourinary system
Diseases of the urinary system
GB90 — Certain specified disorders of kidney or ureter
GB90.4 — Renal tubular function disorders
GB90.4A — Nephrogenic diabetes insipidus

ICD-11 GB90.4A — Nephrogenic diabetes insipidus

Nephrogenic diabetes insipidus is a condition in which the kidney tubules respond poorly to pituitary secreted anti-diuretic hormone, resulting in a failure to concentrate the urine, and water loss. Polyuria with dilute urine and polydypsia (excessive thirst) are present. It can be congenital or acquired with many causes. The congenital forms may be attributed to vasopressin receptor or aquaporin -2 defects. They are characterised by polyuria with polydipsia, recurrent bouts of fever, constipation, and acute hypernatraemic dehydration after birth that may cause neurological sequelae.

The diagnosis includes nothing.

It has no clarifying diagnoses.