ICD-11 classes
03 Diseases of the blood or blood-forming organs
Anaemias or other erythrocyte disorders
Haemolytic anaemias
Acquired haemolytic anaemia
3A20 — Acquired haemolytic anaemia, immune
3A20.1 — Autoimmune haemolytic anaemia, cold type
ICD-11 3A20.1 — Autoimmune haemolytic anaemia, cold type
Cold autoimmune haemolytic anaemia comprises two types of autoimmune haemolytic anaemia (AIHA) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30°C): cold agglutinin disease (CAD), which is the more common, and paroxysmal cold haemoglobinuria (PCH). CAD is more common in people over the age of 55 years, while PCH typically presents in young children. CAD is caused by IgM autoantibodies while PCH is caused by an IgG immunoglobulin.
It includes 1 item.
- Cold haemagglutinin disease
It excludes 2 items.
- Immune thrombocytopenic purpura (3B64.10)
- Haemolytic disease of fetus or newborn (KA84)
It has no clarifying diagnoses.