ICD-11 classes
04 Diseases of the immune system
Nonorgan specific systemic autoimmune disorders
4A41 — Idiopathic inflammatory myopathy
4A41.1 — Polymyositis
4A41.11 — Paraneoplastic polymyositis
ICD-11 4A41.11 — Paraneoplastic polymyositis
Paraneoplastic is a rare cancer associated entity. It presents sub-, or acutely with proximal weakness, often including the neck flexors, dysphagia, rarely the respiratory muscles and the heart are involved. Sometimes muscle pain or myalgia occur. Myopathology shows a targeted, cell-mediated lymphocyte toxicity against muscle fibres in focal areas of inflammation within perimysial connective tissue and surrounding blood vessels. Muscle fibres may be destroyed by cytotoxic T cells.Non-Hodgkin’s lymphoma, lung, and bladder carcinoma are the most frequently observed associated cancer types.
The diagnosis includes nothing.
The diagnosis excludes nothing.
It has no clarifying diagnoses.
The diagnosis is coded elsewhere:
- Polymyositis #7510
- Paraneoplastic or autoimmune disorders of the muscle #7830
- Polymyositis #10078
- Polymyositis #18364