ICD-11 classes
04 Diseases of the immune system
Allergic or hypersensitivity conditions
4A85 — Complex allergic or hypersensitivity conditions
4A85.0 — Drug or pharmacological agents hypersensitivity
4A85.00 — Drug-induced liver hypersensitivity disease

ICD-11 4A85.00 — Drug-induced liver hypersensitivity disease

Drug-induced liver hypersensitivity disease is a relatively rare condition, but can have serious consequences for the individual patient, public health, regulatory agencies and the pharmaceutical industry. It is characterised by elevation in serum alanine-aminotransferase (ALT), conjugated bilirubin, or combined bilirubin, ALT and alkaline phosphatase (AP) levels > 2 times the upper limit of normal (ULN) and the most frequent related drugs are halothane, tienilic acid, dihydralazine, diclofenac, and carbamazepine.

The diagnosis includes nothing.

The diagnosis excludes nothing.

It has no clarifying diagnoses.