ICD-11 classes
05 Endocrine, nutritional or metabolic diseases
Endocrine diseases
Disorders of the adrenal glands or adrenal hormone system
5A70 — Cushing syndrome
5A70.0 — Pituitary-dependent Cushing disease
ICD-11 5A70.0 — Pituitary-dependent Cushing disease
Pituitary-dependent Cushing disease is caused by a pituitary tumour, generally benign (adenoma) but rarely malignant (carcinoma), which secretes adrenocorticotropin (ACTH) autonomously, leading to hypercortisolism. The condition is associated with increased morbidity and mortality that can be mitigated by treatments that result in sustained endocrine remission. Transsphenoidal pituitary surgery (TSS) remains the mainstay of treatment for this disease but requires considerable neurosurgical expertise and experience in order to optimize patient outcomes.
The diagnosis includes nothing.
The diagnosis excludes nothing.
It has no clarifying diagnoses.