ICD-11 classes
05 Endocrine, nutritional or metabolic diseases
Nutritional disorders
Overweight, obesity or specific nutrient excesses
Certain specified nutrient excesses
5B91 — Mineral excesses
5B91.3 — Fluorine excess

ICD-11 5B91.3 — Fluorine excess

The primary adverse effects associated with chronic, excess fluoride intake are enamel and skeletal fluorosis. Enamel fluorosis is a dose-response effect caused by fluoride intake during the pre-eruptive development of teeth. The development of skeletal fluorosis and its severity is directly related to the level and duration of exposure. The clinical signs in advanced stages may include dose-related calcification of ligaments, osteosclerosis, exostoses, possibly osteoporosis of long bones, muscle wasting and neurological defects due to hypercalcification of vertebrae.

The diagnosis includes nothing.

The diagnosis excludes nothing.

It has no clarifying diagnoses.