ICD-11 classes
05 Endocrine, nutritional or metabolic diseases
Nutritional disorders
Nutritional or toxic disorders of the nervous system
8D43 — Neurological disorders due to toxicity
8D43.1 — Cognitive impairment due to toxicity
6D85.2 — Dementia due to exposure to heavy metals and other toxins

ICD-11 6D85.2 — Dementia due to exposure to heavy metals and other toxins

Dementia due to exposure to heavy metals and other toxins caused by toxic exposure to specific heavy metals such as aluminium from dialysis water, lead, mercury or manganese. The characteristic cognitive impairments in Dementia due to exposure to heavy metals and other toxins depend on the specific heavy metal or toxin that the individual has been exposed to but can affect any cognitive domain. Onset of symptoms is related to exposure and progression can be rapid especially with acute exposure. In many cases, symptoms are reversible when exposure is identified and ceases. Investigations such as brain imaging or neurophysiological testing may be abnormal. Lead poisoning is associated with abnormalities on brain imaging including widespread calcification and increased signal on MRI T2-weighted images of periventricular white matter, basal ganglia hypothalamus and pons. Dementia due to aluminium toxicity may demonstrate characteristic paroxysmal high-voltage delta EEG changes. Examination may make evident other features such as peripheral neuropathy in the case of lead, arsenic, or mercury.

The diagnosis includes nothing.

It excludes 1 item.

  • Dementia due to psychoactive substances including medications (6D84)

It has no clarifying diagnoses.

The diagnosis is coded elsewhere:

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