ICD-11 classes
06 Mental, behavioural or neurodevelopmental disorders
Disorders due to substance use or addictive behaviours
Disorders due to substance use
6C42 — Disorders due to use of synthetic cannabinoids
6C42.2 — Synthetic cannabinoid dependence

ICD-11 6C42.2 — Synthetic cannabinoid dependence

Synthetic cannabinoid dependence is a disorder of regulation of synthetic cannabinoid use arising from repeated or continuous use of synthetic cannabinoids. The characteristic feature is a strong internal drive to use synthetic cannabinoids, which is manifested by impaired ability to control use, increasing priority given to use over other activities and persistence of use despite harm or negative consequences. These experiences are often accompanied by a subjective sensation of urge or craving to use synthetic cannabinoids. Physiological features of dependence may also be present, including tolerance to the effects of synthetic cannabinoids, withdrawal symptoms following cessation or reduction in use of synthetic cannabinoids, or repeated use of synthetic cannabinoids or pharmacologically similar substances to prevent or alleviate withdrawal symptoms. The features of dependence are usually evident over a period of at least 12 months but the diagnosis may be made if synthetic cannabinoid use is continuous (daily or almost daily) for at least 3 months.

The diagnosis includes nothing.

It excludes 2 items.

  • Episode of harmful use of synthetic cannabinoids (6C42.0)
  • Harmful pattern of use of synthetic cannabinoids (6C42.1)

Diagnosis with code 6C42.2 contains 6 clarifying diagnoses:

  1. 6C42.20 — Synthetic cannabinoid dependence, current use
  2. 6C42.21 — Synthetic cannabinoid dependence, early full remission
  3. 6C42.22 — Synthetic cannabinoid dependence, sustained partial remission
  4. 6C42.23 — Synthetic cannabinoid dependence, sustained full remission
  5. 6C42.2Y — Other specified synthetic cannabinoid dependence
  6. 6C42.2Z — Synthetic cannabinoid dependence, unspecified

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