ICD-11 classes
08 Diseases of the nervous system
Multiple sclerosis or other white matter disorders
8A41 — Isolated demyelinating syndromes of the central nervous...

ICD-11 8A41 — Isolated demyelinating syndromes of the central nervous system

Clinically isolated syndrome (CIS) is the first clinical inflammatory demyelinating event of the central nervous system, lasting greater than 24 hours CIS is now recognised as the first clinical presentation of a disease that shows characteristics of inflammatory demyelination that could be MS, but has yet to fulfill criteria of dissemination in time.

The diagnosis includes nothing.

The diagnosis excludes nothing.

Diagnosis with code 8A41 contains 5 clarifying diagnoses:

  1. 8A41.0 — Transverse myelitis
  2. 8A41.1 — Neuromyelitis optica myelin oligodendrocyte glycoprotein antibody-positive
  3. 9C40.1 — Optic neuritis
    It contains 4 clarifying diagnoses.
  4. 8A41.Y — Other specified isolated demyelinating syndromes of the central nervous system
  5. 8A41.Z — Isolated demyelinating syndromes of the central nervous system, unspecified

The diagnosis is included in 2 other classes.

  • Optic neuritis (9C40.1)
  • Idiopathic inflammatory optic neuropathy (9C40.1Y)

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