ICD-11 classes
14 Diseases of the skin
Skin disorders involving specific cutaneous structures
Disorders of the epidermis and epidermal appendages
Disorders of epidermal keratinisation
ED51 — Diffuse epidermal hyperkeratosis and acanthosis
ED51.0 — Acanthosis nigricans
ED51.00 — Benign acanthosis nigricans

ICD-11 ED51.00 — Benign acanthosis nigricans

Benign acanthosis nigricans is a thickening and pigmentation affecting predominantly flexural skin, especially the neck, axillae and groins. It is thought to be due to high concentrations of insulin binding to insulin-like growth factor receptors, with resultant keratinocyte proliferation. It is strongly associated with insulin resistance and obesity. Type 2 diabetes and the metabolic syndrome are commonly associated.

The diagnosis includes nothing.

It has no clarifying diagnoses.

The diagnosis is coded elsewhere:

• Cutaneous markers of internal disorders #17427