ICD-11 classes
02 Neoplasms
Malignant neoplasms, except primary neoplasms of lymphoid,...
Malignant neoplasms, stated or presumed to be primary, of...
Malignant mesenchymal neoplasms
2B5B — Gastrointestinal stromal tumour, primary site

ICD-11 2B5B — Gastrointestinal stromal tumour, primary site

This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiation, and most examples contain KIT- or PDGFRA- activating mutations. It is most frequent in the stomach and to a lesser degree in the small intestine. The prognosis depends on the tumour size and the mitotic activity.

The diagnosis includes nothing.

The diagnosis excludes nothing.

Diagnosis with code 2B5B contains 4 clarifying diagnoses:

  1. 2B5B.0 — Gastrointestinal stromal tumour of stomach
  2. 2B5B.1 — Gastrointestinal stromal tumour of small intestine
  3. 2B5B.Y — Gastrointestinal stromal tumour of other gastrointestinal sites
  4. 2B5B.Z — Gastrointestinal stromal tumour of unspecified gastrointestinal sites

The diagnosis is coded elsewhere:

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