ICD-11 classes
03 Diseases of the blood or blood-forming organs
Neoplasms of haematopoietic or lymphoid tissues
Myeloid and lymphoid neoplasms with eosinophilia and...

ICD-11 Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1

A group of rare myeloid and lymphoid neoplasms characterised by rearrangement of the PDGFRA, PDGFRB, or FGFR1 genes, resulting in the formation of fusion transcripts and aberrant tyrosine kinase activity. Eosinophilia is a characteristic finding but it is not always present.

The diagnosis includes nothing.

The diagnosis excludes nothing.

Diagnosis contains 4 clarifying diagnoses:

1. 2A50 — Myeloid/lymphoid neoplasm associated with PDGFRA rearrangement
2. 2A51 — Myeloid neoplasm associated with PDGFRB rearrangement
3. 2A52 — Myeloid or lymphoid neoplasms with FGFR1 abnormalities
4. 2A5Z — Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1, unspecified

The diagnosis is coded elsewhere:

• Neoplasms of haematopoietic or lymphoid tissues #1534
• Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1 #1591