ICD-11 classes
03 Diseases of the blood or blood-forming organs
Neoplasms of haematopoietic or lymphoid tissues
2A60 — Acute myeloid leukaemias and related precursor neoplasms
2A60.4 — Myeloid proliferation associated with Down syndrome
ICD-11 2A60.4 — Myeloid proliferation associated with Down syndrome
Myeloid neoplasms occurring in individuals with Down syndrome. There is an increased risk of acute leukaemias in both children and adults with Down syndrome. In particular, the incidence of acute myeloid leukaemia in Down syndrome children of less than five years of age is particularly high, it is usually an acute megakaryoblastic leukaemia, and is associated with GATA1 gene mutation. This group of disorders also includes the entity transient abnormal myelopoiesis which occurs in neonates and is associated with GATA1 gene mutation.
The diagnosis includes nothing.
The diagnosis excludes nothing.
Diagnosis with code 2A60.4 contains 4 clarifying diagnoses:
- 2A60.40 — Transient abnormal myelopoiesis
- 2A60.41 — Myeloid leukaemia associated with Down syndrome
- 2A60.4Y — Other specified myeloid proliferation associated with Down syndrome
- 2A60.4Z — Myeloid proliferation associated with Down syndrome, unspecified
The diagnosis is coded elsewhere: