ICD-11 classes
03 Diseases of the blood or blood-forming organs
Neoplasms of haematopoietic or lymphoid tissues
Mature B-cell neoplasms
2A83 — Plasma cell neoplasms
2A83.5 — Monoclonal immunoglobulin deposition disease
2A83.50 — Heavy chain deposition disease

ICD-11 2A83.50 — Heavy chain deposition disease

A disease of the kidney, caused by proliferation and deposition of pieces of truncated or abnormal alpha, gamma, delta, or mu immunoglobulin heavy chain segments of white blood cells. This disease is characterised by fibrillar or granular tissue deposits and renal dysfunction, which may lead to organ failure. Confirmation is by identifying heavy chain deposition tissue biopsy using immunofluorescence under a microscope.

The diagnosis includes nothing.

It has no clarifying diagnoses.

The diagnosis is coded elsewhere:

• Monoclonal immunoglobulin deposition disease #1676