ICD-11 classes
08 Diseases of the nervous system
Diseases of neuromuscular junction or muscle
Myasthenia gravis or certain specified neuromuscular...

ICD-11 Myasthenia gravis or certain specified neuromuscular junction disorders

Myasthenia gravis is the most common autoimmune disease affecting the neuromuscular junction and is characterised by painless fatigable muscle weakness. It is caused by autoantibodies against neuromuscular junction proteins, either the nicotinic acetylcholine receptor (AChR) or the muscle specific tyrosine kinase (MuSK). Mutations in neuromuscular junction proteins cause congenital myasthenic syndromes. Other antibodies mediated conditions affecting the neuromuscular junction, including Lambert Eaton myasthenic syndrome and neuromyotonia.

The diagnosis includes nothing.

The diagnosis excludes nothing.

Diagnosis contains 6 clarifying diagnoses:

1. 8C60 — Myasthenia gravis
   It contains 4 clarifying diagnoses.
2. 8C61 — Congenital myasthenic syndromes
3. 8C62 — Lambert-Eaton syndrome
4. 1A11 — Botulism
   It contains 3 clarifying diagnoses.
5. 8C6Y — Other specified myasthenia gravis and neuromuscular junction disorders
6. 8C6Z — Unspecified myasthenia gravis or neuromuscular junction disorders

The diagnosis is coded elsewhere:

• Diseases of neuromuscular junction or muscle #10002
• Myasthenia gravis or certain specified neuromuscular junction disorders #10003